The FERMT3 antibody from Wuhan Fine Biotech Co., Ltd. is a Rabbit Polyclonal antibody to FERM domain containing kindlin 3, and Fermt3. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The FERMT3 antibody has been validated for the following applications: EIA, Immunoassay, ELISA, Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
Plays a central role in cell adhesion in hematopoietic cells(PubMed:19234463, PubMed:26359933). Acts by activating the integrin beta-1-3(ITGB1, ITGB2 and ITGB3)(By similarity). Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells(PubMed:19234460). Required for activation of integrin beta-2(ITGB2) in polymorphonuclear granulocytes(PMNs)(By similarity). Isoform 2 may act as a repressor of NF-kappa-B and apoptosis